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XVA143
1,552 CAD
Only 1000 item(s) left in stock.
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– XVA143, an α/β I-like allosteric antagonist, effectively blocks LFA-1-dependent firm adhesion while simultaneously increasing adhesion under shear flow and rolling conditions, both in vitro and in vivo.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T40274
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H21Cl2N3O8
References
– Azucena Salas, et al. Rolling adhesion through an extended conformation of integrin alphaLbeta2 and relation to alpha I and beta I-like domain interaction. Immunity. 2004 Apr;20(4):393-406.
CAS Number
– 264275-77-6
Molecular Weight
– C25H21Cl2N3O8
SMILES
– OC(=O)[C@H](CNC(=O)c1cc(O)cc(O)c1)NC(=O)c1c(Cl)cc(cc1Cl)C(=O)NCc1cccc(O)c1
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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