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Products Details
Product Description
– XO/COX/LOX-IN-1 (compound 7i) is a potent xanthine oxidase/cyclooxygenases/lipoxygenases (XO/COX/LOX) inhibitor. XO/COX/LOX-IN-1 can be used in studies of inflammation, cancer and metabolic diseases[1].
Web ID
– HY-151173
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C24H20N4O2S
References
– [1]Zabiulla, et al. In-silico docking, synthesis, structure analysis, DFT calculations, energy frameworks, and pharmacological intervention of [1,3,4]-thiadiazoles analogous as XO inhibitor and on multiple molecular inflammatory targets COX and LOX. Journal of Molecular Structure. 2021 Dec;1253(1-2):132272.
CAS Number
– 2831329-35-0
Molecular Weight
– 428.51
SMILES
– CC1=NC2=C(C=CC=C2OCC3=NN=C(COC4=CC=CC5=C4N=C(C=C5)C)S3)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer; Metabolic Disease; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– COX;Lipoxygenase;Xanthine Oxidase
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
