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Thalidomide-5-methyl
$316
Only 1000 item(s) left in stock.
Products Details
Product Description
– Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein[1].
Web ID
– HY-139548
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C14H12N2O4
References
– [1]George W. Muller, et al. Substituted 2-(2,6 dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing TNFα levels. Patent US5874448A.
CAS Number
– 40313-92-6
Molecular Weight
– 272.26
SMILES
– O=C1NC(C(CC1)N2C(C3=CC=C(C)C=C3C2=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ligands for E3 Ligase
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
