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Rottlerin

SKU T16791-5 mg Category Natural Product Brand: TargetMol

Price range: 56 CAD through 189 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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10 mg 25 mg 5 mg

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Products Details

Product Description

– Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase 3 activation.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T16791

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C30H28O8

Citations

– 1. Qin X, Liu B, Gao F, et al. Gluconolactone Alleviates Myocardial Ischemia/Reperfusion Injury and Arrhythmias via Activating PKCε/Extracellular Signal-Regulated Kinase Signaling. Frontiers in Physiology. 2022: 455.

References

– Gschwendt M, et al. Rottlerin, a novel protein kinase inhibitor. Biochem Biophys Res Commun. 1994 Feb 28;199(1):93-8.

CAS Number

– 82-08-6

Molecular Weight

– C30H28O8

Compound Purity

– 0.9944

SMILES

– CC(=O)c1c(O)c(C)c(O)c(Cc2c(O)c3C=CC(C)(C)Oc3c(C(=O)C=Cc3ccccc3)c2O)c1O

Target

– Antibacterial

Pathway

– Apoptosis|||Neuroscience|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||Autophagy|||Microbiology/Virology|||Tyrosine Kinase/Adaptors|||Proteases/Proteasome

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.