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(R)-(+)-Bay-K-8644
$118 – $1,350
Products Details
Product Description
– (R)-(+)-Bay-K-8644 is a calcium channel inhibitor. (R)-(+)-Bay-K-8644 inhibits Ba2+ currents (IBa) (IC50=975 nM).
Web ID
– HY-15125
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C16H15F3N2O4
References
– [1]Zhu HL, et al. Antagonistic actions of S(-)-Bay K 8644 on cyclic nucleotide-induced inhibition of voltage-dependent Ba(2+) currents in guinea pig gastric antrum. Naunyn Schmiedebergs Arch Pharmacol. 2008 Dec;378(6):609-15.|[2]Sidaway P, et al. L-type Ca2+ channel sparklets revealed by TIRF microscopy in mouse urinary bladder smooth muscle. PLoS One. 2014 Apr 3;9(4):e93803.
CAS Number
– 98791-67-4
Molecular Weight
– 356.30
Compound Purity
– 99.69
SMILES
– CC1=C([N+]([O-])=O)[C@H](C2=C(C(F)(F)F)C=CC=C2)C(C(OC)=O)=C(C)N1
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : ≥ 300 mg/mL
Target
– Calcium Channel
Isoform
– L-type calcium channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
