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Guselkumab
$800 – $2,800
Products Details
Product Description
– Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research[1].
Web ID
– HY-P9931
Storage Temperature
– Store at -80°C for 2 years
Shipping
– Dry Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– N/A
References
– [1]International non-proprietary name: guselkumab Procedure No. EMEA/H/C/004271/0000par-public-assessment-report_en.pdf|[2]Li Li, et al. IBI112, a selective anti-IL23p19 monoclonal antibody, displays high efficacy in IL-23-induced psoriasiform dermatitis. Int Immunopharmacol
CAS Number
– 1350289-85-8
Molecular Weight
– N/A
Compound Purity
– 98.97
SMILES
– [Guselkumab]
Clinical Information
– Launched
Research Area
– Inflammation/Immunology
Solubility
– H2O
Target
– Interleukin Related
Isoform
– IL-23
Pathway
– Immunology/Inflammation
Product type
– Inhibitory Antibodies
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
