GPNA hydrochloride

SKU T15411-10 mg Category Brand:

Price range: 50 CAD through 589 CAD

Products Details

Product Description

– GPNA hydrochloride is specific glutamine (Gln) transporter ASCT2(SLC1A5) inhibitor. GPNA reversibly induces apoptosis in A549 cells. GPNA hydrochloride is a well-known substrate of the enzyme γ-glutamyltransferase (GGT). GPNA hydrochloride also inhibits Na+-dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na+-independent leucine transporters LAT1/2.

Web ID

– T15411

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C11H14ClN3O5

References

– Corti A, et al. γ-Glutamyltransferase enzyme activity of cancer cells modulates L-γ-glutamyl-p-nitroanilide (GPNA) cytotoxicity. Sci Rep. 2019 Jan 29;9(1):891.

CAS Number

– 67953-08-6

Molecular Weight

– C11H14ClN3O5

Compound Purity

– 0.9991

SMILES

– Cl.NC(=O)CCC(Nc1ccc(cc1)[N+]([O-])=O)C(O)=O

Target

– Autophagy|||FGFR

Pathway

– Apoptosis

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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