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Products Details
Product Description
– Gentiakochianin (Swertianine), an anthrone from Gentianaceae, has vasodilatory activity, induces glioma cell cycle arrest in the G(2)/M phase and inhibits proliferation, significantly reduces oxLDL-induced cell damage in EA.hy926 cells, inhibits ROS levels and up-regulated the activity of Akt/CREB/eNOS signaling pathway inhibited by oxLDL.
Web ID
– T19932
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C14H10O6
References
– Isakovic A, Jankovic T, Harhaji L, Kostic-Rajacic S, Nikolic Z, Vajs V, Trajkovic V. Antiglioma action of xanthones from Gentiana kochiana: Mechanistic and structure-activity requirements. Bioorg Med Chem. 2008 May 15;16(10):5683-94. doi: 10.1016/j.bmc.2008.03.069. Epub 2008 Mar 30. PubMed PMID: 18406151.
CAS Number
– 20882-75-1
Molecular Weight
– C14H10O6
Compound Purity
– 0.9897
SMILES
– O=C1C2=C(O)C=C(OC)C=C2OC3=CC=C(O)C(O)=C13
Target
– Others
Pathway
– Immunology/Inflammation|||Cytoskeletal Signaling|||Chromatin/Epigenetic|||PI3K/Akt/mTOR signaling
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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