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Etanercept
$400 – $4,100
Products Details
Product Description
– Etanercept, a dimeric fusion protein that binds TNF, acts as a TNF inhibitor. Etanercept competitively inhibits the binding of both TNF-α and TNF-β to cell surface TNF receptors, rendering TNF biologically inactive. Etanercept shows efficacy against rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis[1][2][3].
Web ID
– HY-108847
Storage Temperature
– Store at 4°C for 2 years, do not freeze
Shipping
– Isolate blue ice and the product with bubble pack to avoid direct contact
Applications
– COVID-19-immunoregulation
Molecular Formula
– N/A
References
– [1]Haraoui B, et al. Etanercept in the treatment of rheumatoid arthritis. Ther Clin Risk Manag. 2007;3(1):99-105.|[2]Goffe B, et al. Etanercept: An overview. J Am Acad Dermatol. 2003;49(2 Suppl):S105-S111.|[3]Goldenberg MM. Etanercept, a novel drug for the treatment of patients with severe, active rheumatoid arthritis. Clin Ther. 1999;21(1):75-2.|[4]Totoson P, et al. Etanercept improves endothelial function via pleiotropic effects in rat adjuvant-induced arthritis. Rheumatology (Oxford). 2016;55(7):1308-1317.
CAS Number
– 185243-69-0
Molecular Weight
– 150 kDa(Average)
Compound Purity
– 99.20
SMILES
– [Etanercept]
Clinical Information
– Launched
Research Area
– Inflammation/Immunology; Cancer
Solubility
– H2O
Target
– Bacterial;TNF Receptor
Isoform
– CD40;Fas
Pathway
– Anti-infection;Apoptosis
Product type
– Inhibitory Antibodies
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
