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Edecesertib
$550 – $4,980
Products Details
Product Description
– Edecesertib (GS-5718) is a selective, potent, orally active IRAK-4 inhibitor. Edecesertib has anti-inflammatory activity. Edecesertib can be used for rheumatoid arthritis (RA) and lupus erythematosus (LE) research[1][2].
Web ID
– HY-147264
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H22FN7O2
References
– [1]Roedder S, et, al. Phase 1 Study Results of GS-5718, an Oral IRAK4-Inhibitor: Pharmacodynamics of Single and Multiple Doses of GS-5718 in Healthy Subjects. 2021 Nov 6.|[2]WHO Drug Information. International Nonproprietary Names for Pharmaceutical
CAS Number
– 2408839-73-4
Molecular Weight
– 435.45
Compound Purity
– 99.86
SMILES
– N#C[C@@H](C)NC1=C(C(NC[C@@H](F)C(C)(O)C)=O)C=NC(C2=CC=C3N2N=CC(C#N)=C3)=C1
Clinical Information
– Phase 2
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– IRAK
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
