(E/Z)-Zotiraciclib
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(E/Z)-Zotiraciclib

SKU T21503-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 61 CAD through 853 CAD

Products Details

Product Description

– (E/Z)-Zotiraciclib ((E/Z)-TG02) effectively inhibits CDK2, JAK2, and FLT3 with IC50s of 13 nM, 73 nM, and 56 nM, respectively.

Web ID

– T21503

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H24N4O

References

– William AD, et al. Discovery of kinase spectrum selective macrocycle (16E)-14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a potent inhibitor of cyclin dependent kina

CAS Number

– 937270-47-8

Molecular Weight

– C23H24N4O

Compound Purity

– 0.9912

SMILES

– CN1CC2=CC(N=C3NC(C=4C=C(C=CC4)OCCC=CC1)=CC=N3)=CC=C2

Pathway

– Angiogenesis|||Chromatin/Epigenetic|||Cell Cycle/Checkpoint|||Stem Cells|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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