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Dehydrocorydaline
Price range: 83 CAD through 1,341 CAD
Products Details
Product Description
– 1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimerization of MyoD and E proteins, thus resulting in MyoD activation and myoblast differentiation. 3. Dehydrocorydaline shows antiplatelet effects, it inhibits thrombin-induced platelet aggregation in a low dose ( IC50= 34.914 ug/mL). 4. Dehydrocorydaline has anti-inflammatory and antinociceptive effects. 5. Dehydrocorydaline inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP.
Web ID
– T5S2358
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H24NO4
References
– Lee J , Sohn E J , Yoon S W , et al. Anti-Metastatic Effect of Dehydrocorydaline on H1299 Non-Small Cell Lung Carcinoma Cells via Inhibition of Matrix Metalloproteinases and B Cell Lymphoma 2[J]. Phytotherapy Research, 2017, 31(3):441-448.
CAS Number
– 30045-16-0
Molecular Weight
– C22H24NO4
Compound Purity
– 0.9984
SMILES
– CC1=C2C=3C(=CC(OC)=C(OC)C3)CC[N+]2=CC=4C1=CC=C(OC)C4OC
Pathway
– Proteases/Proteasome|||Autophagy|||Apoptosis|||Chromatin/Epigenetic|||MAPK|||Microbiology/Virology|||DNA Damage/DNA Repair
Product type
– Natural Product
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