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Degrasyn
Price range: 59 CAD through 1,258 CAD
Products Details
Product Description
– Degrasyn (WP1130) (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor, also inhibits Bcr/Abl, which is a JAK2 transducer (without affecting 20S proteasome) and activator of transcription (STAT).
Web ID
– T6300
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H18BrN3O
Citations
– 1. Luo H, Jing B, Xia Y, et al. WP1130 reveals USP24 as a novel target in T-cell acute lymphoblastic leukemia. Cancer Cell International. 2019 Mar 13;19:56
2. Yan B, Guo J, Wang Z, et al.The ubiquitin‐specific protease 5 mediated deubiquitination of LSH links metabolic regulation of ferroptosis to hepatocellular carcinoma progression.MedComm.2023, 4(4): e337.
References
– Bartholomeusz GA, et al. Blood, 2007, 109(8), 3470-3478.
CAS Number
– 856243-80-6
Molecular Weight
– C19H18BrN3O
Compound Purity
– 0.9998
SMILES
– CCC[C@H](NC(=O)C(=Cc1cccc(Br)n1)C#N)c1ccccc1
Pathway
– Angiogenesis|||Autophagy|||Cytoskeletal Signaling|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Apoptosis|||Ubiquitination|||Stem Cells|||Chromatin/Epigenetic|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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