Download Files:
Products Details
Product Description
– Cnicin is a sesquiterpene lactone. Cnicin has antiproliferative effects, and induces cell death in primary myeloma cells. Cnicin also has anti-SARS-CoV-2 activity. Cnicin inhibits viral replication of SARS CoV-2 with an IC50 of 1.18 μg/mL[1].
Web ID
– HY-137984
Shipping
– Room temperature
Molecular Formula
– C20H26O7
References
Р[1]Alhadrami HA, et al. Cnicin as an Anti-SARS-CoV-2: An Integrated In Silico and In Vitro Approach for the Rapid Identification of Potential COVID-19 Therapeutics. Antibiotics (Basel). 2021 May 7;10(5):542.|[2]J̦hrer K, et al. Antimyeloma activity of the sesquiterpene lactone cnicin: impact on Pim-2 kinase as a novel therapeutic target. J Mol Med (Berl). 2012 Jun;90(6):681-93.
CAS Number
– 24394-09-0
Molecular Weight
– 378.42
SMILES
– O=C(C([C@@H](O)CO)=C)O[C@@H](C/C(C)=C/CC1)[C@](C2=C)([H])[C@@](OC2=O)([H])/C=C1CO
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– SARS-CoV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
