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BD-Oligo
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– BD-Oligo is a promising fluorescent sensor designed for detecting Aβ oligomers. It effectively monitors the dynamics of these oligomers during fibril formation in vitro and shows potential for in vivo staining in Alzheimer’s disease (AD) mouse models. The sensing mechanism is facilitated through π-π stacking interactions and hydrogen bonding between BD-Oligo and the exposed hydrophobic regions of Aβ oligomers, as confirmed by computational techniques. Furthermore, BD-Oligo can cross the blood-brain barrier (BBB) to detect oligomers in the brains of AD transgenic mice without causing toxicity.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T202001
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H24BCl3F2N2O4
CAS Number
– 1357578-02-9
Molecular Weight
– C25H24BCl3F2N2O4
SMILES
– C(=C/C1=C(O)C(OCC)=CC=C1)C2=[N]3C(=CC=4[N-]([B+3]3([F-])[F-])C(CCC(OCC(Cl)(Cl)Cl)=O)=CC4)C(C)=C2
Target
– Others
Product type
– Dye-Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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