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Bay 41-4109
Price range: 618 CAD through 6,688 CAD
Products Details
Product Description
– BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
Web ID
– T10480L
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H13ClF3N3O2
Citations
– 1. Yang Y, Yan Y, Yin J, et al. Structure-Based Discovery of N-Sulfonylpiperidine-3-carboxamides as Novel Capsid Assembly Modulators for Potent Inhibition of HBV Replication. Viruses. 2022, 14(2): 348.
2. Yin J, Feng Z, Li Z, et al.Synthesis and evaluation of N-sulfonylpiperidine-3-carboxamide derivatives as capsid assembly modulators inhibiting HBV in vitro and in HBV-transgenic mice.European Journal of Medicinal Chemistry.2023: 115141.
References
– Weber O, et al. Inhibition of human hepatitis B virus (HBV) by a novel non-nucleosidic compound in a transgenic mouse model. Antiviral Res. 2002 May;54(2):69-78.
CAS Number
– 298708-81-3
Molecular Weight
– C18H13ClF3N3O2
SMILES
– COC(=O)C1=C(C)N=C(N[C@H]1c1ccc(F)cc1Cl)c1ncc(F)cc1F
Target
– Others
Pathway
– Microbiology/Virology
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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