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AZD4635
Price range: 50 CAD through 1,696 CAD
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T4265
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H11ClFN5
Citations
– 1. Kang G, Zhao X, Sun J, et al.A2AR limits IL-15-induced generation of CD39+ NK cells with high cytotoxicity.International Immunopharmacology.2023, 114: 109567.
References
– Alexandra Borodovsky, et al. Abstract 5580: PreClinicalal pharmacodynamics and antitumor activity of AZD4635, a novel adenosine 2A receptor inhibitor that reverses adenosine mediated T cell suppression. AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 5580.
CAS Number
– 1321514-06-0
Molecular Weight
– C15H11ClFN5
Compound Purity
– 0.9961
SMILES
– Cc1cc(cc(Cl)n1)-c1nnc(N)nc1-c1ccc(F)cc1
Pathway
– GPCR/G Protein|||Neuroscience
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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