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Allopurinol riboside

$68$201

Products Details

Product Description

– Allopurinol riboside, a metabolite of allopurinol, shows potent activities against parasites.

Web ID

– HY-101397

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C10H12N4O5

References

– [1]Nishida Y, et al. Inhibition of purine nucleoside phosphorylase activity and of T-cell function with allopurinol-riboside. Agents Actions. 1979 Dec;9(5-6):549-52.|[2]Pacher P, et al. Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol. Pharmacol Rev. 2006 Mar;58(1):87-114.|[3]Shapiro TA, et al. Pharmacokinetics and metabolism of allopurinol riboside. Clin Pharmacol Ther. 1991 May;49(5):506-14.|[4]Were JB, et al. Effects of probenecid on the pharmacokinetics of allopurinol riboside. Antimicrob Agents Chemother. 1993 May;37(5):1193-6.

CAS Number

– 16220-07-8

Molecular Weight

– 268.23

Compound Purity

– 99.04

SMILES

– O=C1C(C=NN2[C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)=C2N=CN1

Clinical Information

– Launched

Research Area

– Infection

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Drug Metabolite;Endogenous Metabolite;Parasite

Isoform

– Leishmania

Pathway

– Anti-infection;Metabolic Enzyme/Protease

Product type

– Natural Products

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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