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Products Details
Product Description
– ALK5-IN-7 is a potent inhibitor of ALK5. Transforming growth factor beta (TGF-β) is a multifunctional cytokine that is involved in regulating cell proliferation, differentiation and apoptosis through complex receptor signaling pathways on the cell surface in an autocrine, paracrine and endocrine manner. ALK5-IN-7 has the potential for the research of TGF-β-related diseases and conditions, including but not limited to tumors, fibrotic diseases, inflammatory diseases, autoimmune diseases, etc (extracted from patent WO2021129621A1, compound 4)[1].
Web ID
– HY-142949
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C26H28N4O3S
References
– [1]Tang Feng, et al. Pyrazoles. Patent WO2021129621A1.
CAS Number
– 2657720-07-3
Molecular Weight
– 476.59
SMILES
– OC(C)(C)C1=NC=CC(C2=CC3=NC=CC(OC4=CN(C5CC5)N=C4C6CCOCC6)=C3S2)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– TGF-β Receptor
Pathway
– TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
