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Products Details
Product Description
– ALK5-IN-30 (EX-07) is a potent ALK inhibitor, inhibits ALK5 and TGFβ-R1 with both IC50s <10 nM[1].
Web ID
– HY-151279
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H25FN8
References
– [1]Petermann Oliver, et al. Preparation of carboxymethyl cellulose having improved storage stability: World Intellectual Property Organization, WO2022162133[P]. 2022-08-04.
CAS Number
– 2785430-86-4
Molecular Weight
– 444.51
SMILES
– CN1CCN(C2=CC=C(NC3=NC=CC(NC4=C5C=C(F)C=C(C)C5=NN=C4)=N3)C=C2)CC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Anaplastic lymphoma kinase (ALK)
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
