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AL-611

Products Details

Product Description

– AL-611 is an HCV NS5B polymerase inhibitor (EC50 = 5 nM).

Web ID

– HY-145374

Shipping

– Room temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C25H33F2N6O8P

References

– [1]Wang G, et al. Synthesis and Anti-HCV Activity of Sugar-Modified Guanosine Analogues: Discovery of AL-611 as an HCV NS5B Polymerase Inhibitor for the Treatment of Chronic Hepatitis C. J Med Chem. 2020 Sep 24;63(18):10380-10395.

CAS Number

– 2481279-61-0

Molecular Weight

– 614.54

SMILES

– C[C@@]1([C@](O[C@@](F)([C@H]1O)CO[P@](OC2=CC=CC=C2)(N[C@@H](C)C(OC(C)C)=O)=O)([H])N3C4=NC(N)=NC(OCC)=C4N=C3)F

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– HCV Protease

Pathway

– Anti-infection;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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