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4-Octyl itaconate

SKU T4580-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 48 CAD through 93 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)100 mg 25 mg 50 mg

Clear

Products Details

Product Description

– 4-Octyl Itaconate, a cell-permeable derivative of Itaconate, is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 and inhibits phosphorylation of STING.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T4580

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C13H22O4

Citations

– 1. Wang S J, Ye W, Li W Y, et al.Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation.Journal of Ethnopharmacology.2022: 116053. 2. Wang Z, Cui L, Lin Y, et al.Cancer cell-intrinsic biosynthesis of itaconate promotes tumor immunogenicity.The EMBO Journal.2024: 1-18.

References

– Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAPNature. 2018 Apr 5;556(7699):113-117.

CAS Number

– 3133-16-2

Molecular Weight

– C13H22O4

Compound Purity

– 0.9994

SMILES

– C(CC(C(O)=O)=C)(OCCCCCCCC)=O

Pathway

– Immunology/Inflammation

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.