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1-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine

Products Details

Product Description

– 1-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

Web ID

– HY-152399

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C18H18F3N5O4

References

– [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.|[2]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Molecular Weight

– 425.36

SMILES

– O[C@@H]1[C@@H](O)[C@@H](CO)O[C@H]1N(C=N2)C3=C2C(NCC4=CC=CC(C(F)(F)F)=C4)=NC=N3

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Nucleoside Antimetabolite/Analog

Pathway

– Cell Cycle/DNA Damage

Product type

– Oligonucleotides

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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