Tolebrutinib
Add to CompareAdded to Compare

Download Files:

Tolebrutinib

SKU T9125-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 58 CAD through 1,107 CAD

Products Details

Product Description

– Tolebrutinib (PRN2246) is a potent, selective, orally active and brain-penetrant Bruton tyrosine kinase (BTK) inhibitor(IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively). It exhibits efficacy in central nervous system immunity. Tolebrutinib can be used for the research of multiple sclerosis (MS).

Web ID

– T9125

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H25N5O3

References

– Reich DS, et al. Safety and efficacy of tolebrutinib, an oral brain-penetrant BTK inhibitor, in relapsing multiple sclerosis: a phase 2b, randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2021 Sep;20(9):729-738.

CAS Number

– 1971920-73-6

Molecular Weight

– C26H25N5O3

Compound Purity

– 0.992

SMILES

– Nc1nccc2n([C@@H]3CCCN(C3)C(=O)C=C)c(=O)n(-c3ccc(Oc4ccccc4)cc3)c12

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

Related Products

Select options
Iron(II) fumarate
Iron(II) fumarate Price range: 48 CAD through 128 CAD
1 g10 g5 g

1000 in stock

Read more
(R)-(+)-Atenolol
(R)-(+)-Atenolol
Select options
3-Acetylcoumarin
3-Acetylcoumarin 46 CAD
1 mL * 10 mM (in DMSO)500 mg

1000 in stock

Select options
4-Methoxycoumarine
4-Methoxycoumarine Price range: 56 CAD through 266 CAD
1 g1 mL * 10 mM (in DMSO)50 mg

1000 in stock

Select options
7-Methoxy-1-tetralone
7-Methoxy-1-tetralone Price range: 46 CAD through 56 CAD
1 g1 mL * 10 mM (in DMSO)

1000 in stock

My Cart
Wishlist
Recently Viewed
Categories

Request Data Sheet / Safty Data Sheet

Please enable JavaScript in your browser to complete this form.
=

Price Request

Please enable JavaScript in your browser to complete this form.
=

Compare Products (0 Products)
document.addEventListener('elementor/popup/show', function() { if (typeof turnstile !== 'undefined') { document.querySelectorAll('.cf-turnstile').forEach(function(el) { if (!el.dataset.rendered) { turnstile.render(el); el.dataset.rendered = true; } }); } });