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Thalidomide-propargyl

SKU T18831-5 mg Category PROTAC Brand: TargetMol

Price range: 61 CAD through 714 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– Thalidomide-propargyl, a Thalidomide-derived Cereblon ligand, facilitates the recruitment of Cereblon. It can be attached to the protein ligand via a linker, producing IMiD-containing PROTACs.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T18831

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H12N2O5

References

– Wurz RP, et al. A “Click Chemistry Platform” for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.

CAS Number

– 2098487-39-7

Molecular Weight

– C16H12N2O5

Compound Purity

– 0.9514

SMILES

– O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC#C

Target

– Dehydrogenase

Pathway

– PROTAC

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.