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H2DCFDA
Price range: 48 CAD through 112 CAD
Products Details
Product Description
– H2DCFDA (DCFH-DA) belongs to the class of green fluorescent dyes and is a probe for the detection of intracellular reactive oxygen species (ROS) (Ex/Em=488/525 nm) with cell membrane permeability.
Web ID
– T15458
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H16Cl2O7
Citations
– 1. Zhang J, Liu P, Chen J, et al. Upgrade of chrysomycin A as a novel topoisomerase II inhibitor to curb KRAS-mutant lung adenocarcinoma progression. Pharmacological Research. 2022: 106565.
2. Hu Y, Wen Q, Cai Y, et al. Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway. Phytomedicine. 2022: 154528.
3. Zhang Y, Cai Y, Wang T, et al.A common tolerance mechanism of bacterial biofilms to antibiotics.bioRxiv.2023: 2023.01. 30.526163.
4. Pan Y, Wang X, Tan Q, et al.Effects and Mechanisms of Prussian Blue Nanozymes with Multiple Enzyme Activities on Nasopharyngeal Carcinoma Cells.Tissue and Cell.2024: 102316.
5. Guo Y, Zhu L, Duan Y, et al.Ruxolitinib induces apoptosis and pyroptosis of anaplastic thyroid cancer via the transcriptional inhibition of DRP1-mediated mitochondrial fission.Cell Death & Disease.2024, 15(2): 125.
6. Zhou X, Qin M, He L, et al.Geraniin restricts inflammasome activation and macrophage pyroptosis by preventing the interaction between ASC and NLRP3 to exert anti-inflammatory effects.International Immunopharmacology.2024, 129: 111656.
7. Yong Y Y, Yan L, Wang B D, et al.Penthorum chinense Pursh inhibits ferroptosis in cellular and Caenorhabditis elegans models of Alzheimer’s disease.Phytomedicine.2024: 155463.
8. Liu Z, Dang B, Li Z, et al.Baicalin attenuates acute skin damage induced by ultraviolet B via inhibiting pyroptosis.Journal of Photochemistry and Photobiology B: Biology.2024: 112937.
9. Li X, Mao C, Sun G, et al.Oleic and linoleic acids induce oxidative stress in chondrocytes by inhibiting autophagy‐regulated ciliogenesis.View.2024: 20240019.
10. Zhang Y, Cai Y, Jin X, et al.Persistent glucose consumption under antibiotic treatment protects bacterial community.Nature Chemical Biology.2024: 1-9.
References
– Lyublinskaya OG, et al. Redox environment in stem and differentiated cells: A quantitative approach. Redox Biol. 2017 Aug;12:758-769.
CAS Number
– 4091-99-0
Molecular Weight
– C24H16Cl2O7
Compound Purity
– 0.9868
SMILES
– CC(=O)Oc1cc2Oc3cc(OC(C)=O)c(Cl)cc3C(c2cc1Cl)c1ccccc1C(O)=O
Target
– Others
Pathway
– Metabolism|||Immunology/Inflammation|||NF-κB
Product type
– Dye-Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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