Ellagic acid
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Ellagic acid

SKU T0465-1 g Category Brand:

Price range: 70 CAD through 232 CAD

Products Details

Product Description

– Ellagic acid (Gallogen), a thickened tetracyclic natural product, is a potent CK2 inhibitor (IC50=40 nM; Ki=20 nM) with ATP-competitive properties. Ellagic acid is an antioxidant and also possesses antiproliferative activity.

Web ID

– T0465

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H6O8

Citations

– 1. Hwang Y H, Jang S A, Kim T, et al. Anti-osteoporotic and Anti-adipogenic Effects of Rhus chinensis Nutgalls in Ovariectomized Mice Fed with a High-fat Diet. Planta Medica. 2019, 85(14/15): 1128-1135 2. Wu Z, Hu L, Ru K, et al.Ellagic Acid inhibits CDK12 to increase osteoblast differentiation and alleviate osteoporosis in hindlimb-unloaded and ovariectomized mice.Phytomedicine.2023: 154745. 3. Hu Q, Wang S, Cheng R, et al.Tannins in Phyllanthus emblica L. improves Cisplatin efficacy in lung cancer cells by boosting endoplasmic reticulum stress to trigger Immunogenic Cell Death.Phytomedicine.2023: 155219. 4. Seo J, Hwang Y H, Lee A, et al.Ethanolic Extract of Bergenia purpurascens Exhibits Antimelanogenic Effects in B16F10 Cells through Multiple Mechanisms That Suppress Tyrosinase.Journal of Agricultural and Food Chemistry.2024

References

– Sekiguchi Y, et al. Bioorg Med Chem Lett. 2009 Jun 1;19(11):2920-3.

CAS Number

– 476-66-4

Molecular Weight

– C14H6O8

Compound Purity

– 0.9976

SMILES

– OC1=CC2=C3C(OC(=O)C4=CC(O)=C(O)C(OC2=O)=C34)=C1O

Target

– Calcium Channel

Pathway

– Chromatin/Epigenetic|||Cytoskeletal Signaling|||Angiogenesis|||Stem Cells|||Immunology/Inflammation|||DNA Damage/DNA Repair|||Tyrosine Kinase/Adaptors|||GPCR/G Protein|||Metabolism|||NF-κB

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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