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Asfotase alfa

SKU HY-108786-1 mg Category Tags ,

$400$990

Products Details

Product Description

– Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2−/− knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP)[1].

Web ID

– HY-108786

Storage Temperature

– Store at -80°C for 2 years

Shipping

– Dry Ice

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– N/A

References

– [1]Yadav MC, et al. Dose response of bone-targeted enzyme replacement for murine hypophosphatasia. Bone. 2011 Aug;49(2):250-6.

CAS Number

– 1174277-80-5

Molecular Weight

– N/A

Compound Purity

– 97.88

SMILES

– [Asfotase alfa]

Clinical Information

– Phase 4

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Others

Pathway

– Others

Product type

– Inhibitory Antibodies

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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