Download Files:

USP28-IN-3

SKU T74793-1 mg Category Small Compound Brand: TargetMol

Price range: 293 CAD through 3,168 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 10 mg 100 mg 25 mg 5 mg 50 mg

Clear

Products Details

Product Description

– USP28-IN-3 is a highly selective USP28 inhibitor with an IC50 value of 0.1 μM against USP28.USP28-IN-3 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3, and UCHL5.USP28-IN-3 is cytotoxic to human colorectal and lung squamous carcinoma cells, inhibiting c-cells and c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-cells through the ubiquitin-proteasome system. -proteasome system to dose-dependently downregulate cellular levels of c-Myc.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T74793

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H20Cl2N2O3S

References

– Zhou D, et al. Structure-based discovery of potent USP28 inhibitors derived from Vismodegib. Eur J Med Chem. 2023 Jun 5;254:115369.

CAS Number

– 2931509-14-5

Molecular Weight

– C23H20Cl2N2O3S

Compound Purity

– 0.9992

SMILES

– O=C(NC1=CC=C(Cl)C(=C1)C=2C=CC3=C(C2)CCNC3)C4=CC=C(C=C4Cl)S(=O)(=O)C

Pathway

– Cell Cycle/Checkpoint|||Ubiquitination|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.