Topoisomerase I/II inhibitor 8

Name: Topoisomerase I/II inhibitor 8 | II | Immunomart
Brand: TargetMol
SKU: T204994-10 mg

SKU T204994-10 mg Category Small Compound Brand: TargetMol

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– TopoisomeraseI/II inhibitor 8 (Compound Ru7) is a dual catalytic inhibitor of TopoisomeraseI/II that induces DNA damage and activates PARP-1, leading to the activation of RIPK1, RIPK3, and MLKL, ultimately causing necroptosis. It shows significant anticancer activity by effectively targeting cancer cell nuclei and inducing cell death through necroptosis, offering substantial clinical potential in overcoming resistance in cancer treatment.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T204994

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H11Br2NO5S2

CAS Number

– 355400-87-2

Molecular Weight

– C14H11Br2NO5S2

SMILES

– O=C(O)CN1C(=O)C(SC1=S)=CC2=CC(OCC)=C(O)C(Br)=C2Br

Pathway

– Apoptosis|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||NF-κB

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.