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Tesmilifene (fumarate)
$40 – $240
Products Details
Product Description
– Tesmilifene fumarate (DPPE fumarate), an H1C receptor antagonist, potentiates a wide range of cytotoxics and even to offer some protection of normal cells[1][2].
Web ID
– HY-101179
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H29NO5
References
– [1]Mark Vincent, et al. Tesmilifene may enhance breast cancer chemotherapy by killing a clone of aggressive, multi-drug resistant cells through its action on the p-glycoprotein pump. Med Hypotheses. 2006;66(4):715-31.|[2]G Sturman, et al. Modulation of the intracellular and H3-histamine receptors and chemically-induced seizures in mice Agents Actions. 1994 Jun;41 Spec No:C68-9.
CAS Number
– 1185241-83-1
Molecular Weight
– 399.48
Compound Purity
– 99.69
SMILES
– CCN(CC)CCOC1=CC=C(CC2=CC=CC=C2)C=C1.O=C(O)/C=C/C(O)=O
Clinical Information
– Phase 2
Research Area
– Cancer; Inflammation/Immunology; Neurological Disease
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Histamine Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
