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STAT3-IN-18
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the JAK2-STAT3 pathway in breast cancer (BC) cells and exhibits anti-proliferative properties. It promotes apoptosis by activating caspase-3 and elevating levels of cleaved polyADP-ribose polymerase, in addition to enhancing maturation and antigen presentation in dendritic cells. Moreover, STAT3-IN-18 has demonstrated in vivo safety.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T79609
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H24Cl2N2O6Pt
CAS Number
– 2668267-41-0
Molecular Weight
– C18H24Cl2N2O6Pt
SMILES
– C(=C/C1=CC=C(OCC([O-][Pt+4]([Cl-])([Cl-])([NH3])([NH3])[OH-])=O)C=C1)C2=CC(OC)=CC(OC)=C2
Pathway
– Stem Cells|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Chromatin/Epigenetic|||Angiogenesis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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