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S3I-201

SKU T2505-5 mg Category Small Compound Brand: TargetMol

Price range: 80 CAD through 674 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– S3I-201 (S3I-201) is a selective Stat3 inhibitor (IC50: 86±33 μM) and low effect towards STAT1/5.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2505

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H15NO7S

Citations

– 1. Xue J, Liao Q, Luo M, et al. Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation. Open Biology. 2022, 12(4): 210310 2. Chen X J, He M J, Zhou G. All‐trans retinoic acid induces anti‐tumor effects via STAT 3 signaling inhibition in oral squamous cell carcinoma and oral dysplasia. Journal of Oral Pathology & Medicine.. 2019

References

– Siddiquee K, et al. Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7391-6.

CAS Number

– 501919-59-1

Molecular Weight

– C16H15NO7S

Compound Purity

– 0.9783

SMILES

– Cc1ccc(cc1)S(=O)(=O)OCC(=O)Nc1ccc(C(O)=O)c(O)c1

Pathway

– JAK/STAT signaling|||Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.