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Rosuvastatin

SKU T1676-5 mg Category Small Compound Brand: TargetMol

Price range: 72 CAD through 626 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR) (IC50=11 nM), selective and competitive. Rosuvastatin has hypolipidemic and antiatherosclerotic effects.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1676

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H28FN3O6S

Citations

– 1. Zhang W, Pan X, Xu Y, et al.Mevalonate improves anti-PD-1/PD-L1 efficacy by stabilizing CD274 mRNA.Acta Pharmaceutica Sinica B.2023 2. Li W, Iusuf D, Sparidans R W, et al.Organic anion-transporting polypeptide 2B1 knockout and humanized mice; insights into the handling of bilirubin and drugs.Pharmacological Research.2023: 106724. 3. Li W, Sparidans R W, Wang Y, et al.Interplay of OATP1A/1B/2B1 uptake transporters and ABCB1 and ABCG2 efflux transporters in the handling of bilirubin and drugs.Biomedicine & Pharmacotherapy.2024, 175: 116644.

References

– Watanabe M, et al. Bioorg Med Chem, 1997, 5(2), 437-444.

CAS Number

– 287714-41-4

Molecular Weight

– C22H28FN3O6S

Compound Purity

– 0.9981

SMILES

– CC(C)c1nc(nc(-c2ccc(F)cc2)c1C=C[C@@H](O)C[C@@H](O)CC(O)=O)N(C)S(C)(=O)=O

Target

– Potassium Channel

Pathway

– Membrane transporter/Ion channel|||Autophagy|||Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.