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RN486

SKU T1976-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 123 CAD through 1,325 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– RN486 is an effective and specific BTK inhibitor (IC50: 4 nM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1976

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C35H35FN6O3

Citations

– 1. Huang F, Liang J, Lin Y, et al.Repurposing of Ibrutinib and Quizartinib as potent inhibitors of necroptosis.Communications Biology.2023, 6(1): 972.

References

– Xu D, et al. J Pharmacol Exp Ther, 2012, 341(1), 90-103.

CAS Number

– 1242156-23-5

Molecular Weight

– C35H35FN6O3

Compound Purity

– 0.9938

SMILES

– CN1CCN(CC1)c1ccc(Nc2cc(cn(C)c2=O)-c2cccc(c2CO)-n2ccc3cc(cc(F)c3c2=O)C2CC2)nc1

Target

– Others

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.