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Products Details
Product Description
– (Rac)-Tezacaftor ((Rac)-VX-661) is a racemate of Tezacaftor (HY-15448). Tezacaftor is a F508del CFTR corrector. (Rac)-Tezacaftor can be used for the research of cystic fibrosis[1].
Web ID
– HY-15448A
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C26H27F3N2O6
References
– [1]Keating D, et al. VX-445-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles. N Engl J Med. 2018 Oct 25;379(17):1612-1620.
CAS Number
– 1226709-85-8
Molecular Weight
– 520.50
SMILES
– FC1=C(NC(C2(CC2)C3=CC4=C(OC(F)(F)O4)C=C3)=O)C=C(C=C5C(C)(C)CO)C(N5CC(O)CO)=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– CFTR
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
