Download Files:

PT-2385

SKU T7848-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 98 CAD through 1,856 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

Clear

Products Details

Product Description

– PT-2385 is a selective inhibitor of HIF-2α with a dissociation constant (Kd) of less than 50 nM (Kd<50 nM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T7848

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H12F3NO4S

Citations

– 1. Li C, Wei Y, Wang P, et al.Screening and Identification of Hypoxia-Inducible Factor Signaling Inhibitor with Antiangiogenic Activity.Pharmaceutical Fronts.2024

References

– Eli Wallace, Ph.D. PT2385: HIF-2α Antagonist for the Treatment of VHL Mutant ccRCC. 12th International VHL Medical Symposium April 8, 2016.

CAS Number

– 1672665-49-4

Molecular Weight

– C17H12F3NO4S

Compound Purity

– 0.9955

SMILES

– CS(=O)(=O)c1ccc(Oc2cc(F)cc(c2)C#N)c2CC(F)(F)[C@@H](O)c12

Pathway

– Metabolism|||Angiogenesis|||Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.