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PMMB-187

SKU T200126-25 mg Category Small Compound Brand: TargetMol

Price range: 4,688 CAD through 7,408 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

100 mg 25 mg 50 mg

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Products Details

Product Description

– PMMB-187, a selective STAT3 inhibitor, exhibits an IC50 of 1.81 μM in MDA-MB-231 cells. This compound induces apoptosis in MDA-MB-231 cells by inhibiting STAT3 transcriptional activity and nuclear translocation, reducing mitochondrial membrane potential, increasing reactive oxygen species (ROS) production, and upregulating the expression of apoptosis-related proteins. PMMB-187 is useful for research in the field of cancer.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T200126

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H23BrN2O6S2

CAS Number

– 2162952-37-4

Molecular Weight

– C27H23BrN2O6S2

SMILES

– O=C1C=2C(C(=O)C=C1[C@H](OC(CSC=3SC(CC4=CC=C(Br)C=C4)=NN3)=O)CC=C(C)C)=C(O)C=CC2O

Target

– Others

Pathway

– JAK/STAT signaling|||Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.