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Pim-1/2 kinase inhibitor 1
$260 – $1,280
Products Details
Product Description
– Pim-1/2 kinase inhibitor 1 is an orally active pim-1/2 kinase inhibitor. Pim-1/2 kinase inhibitor 1 blocks the ability of Pim kinases to phosphorylate peptides, and inhibits the pim protein kinase directed phosphorylation of 4E-BP1 and p27Kip1. Pim-1/2 kinase inhibitor 1 can be used in study of cancer, especially prostate cancer[1].
Web ID
– HY-W412264
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C11H9NO3S
References
– [1]Charles D. Smith, et al. Inhibitors of PIM-1 Protein Kinases, Compositions and Methods for Treating Prostate Cancer. Patent US20110263664A1.
CAS Number
– 6320-51-0
Molecular Weight
– 235.26
Compound Purity
– 99.90
SMILES
– O=C(NC1=O)SC1=CC2=CC=C(OC)C=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 250 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Pim
Pathway
– JAK/STAT Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
