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OXA-11

SKU T28277-1 mg Category Small Compound Brand: TargetMol

Price range: 2,544 CAD through 6,864 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– OXA-11 (FAK-IN-16) is an orally active, selective focal adhesion kinase (FAK) inhibitor with antitumor activity. It inhibits FAK phosphorylation at tyrosine 397 in a dose-dependent manner and suppresses TOV21G tumor growth. It is used in cancer research.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T28277

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C37H49F3N7O5P

References

– Moen I, Gebre M, Alonso-Camino V, Chen D, Epstein D, McDonald DM. Anti-metastatic action of FAK inhibitor OXA-11 in combination with VEGFR-2 signaling blockade in pancreatic neuroendocrine tumors. Clin Exp Metastasis. 2015 Dec;32(8):799-817. doi: 10.1007/s10585-015-9752-z. PubMed PMID: 26445848; PubMed Central PMCID: PMC4651821.

CAS Number

– 1257994-15-2

Molecular Weight

– C37H49F3N7O5P

Compound Purity

– 0.987

SMILES

– N(C1=C2C(=C(C=C1)[C@H]3CC[C@@H](CC3)N4CCN(C)CC4)CN(C)C2=O)C=5C(C(F)(F)F)=CN=C(NC6=C(OC)C=C(CP(OCC)(OCC)=O)C=C6)N5

Pathway

– Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.