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NMS-873

SKU T1853-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 62 CAD through 926 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– NMS-873 is a potent and selective allosteric inhibitor of VCP/p97.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1853

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H28N4O3S2

Citations

– 1. Du, Yuanjiao, et al. VPS13D interacts with VCP/p97 and negatively regulates ER-mitochondrial interactions. Molecular Biology of the Cell. (2021): mbc-E21 2. Xie S, Liu H, Zhu S, et al.Arsenic trioxide and p97 inhibitor synergize against acute myeloid leukemia by targeting nascent polypeptides and activating the ZAKα–JNK pathway.Cancer Gene Therapy.2024: 1-12.

References

– Magnaghi P, et al. Nat Chem Biol. 2013, 9(9), 548-556.

CAS Number

– 1418013-75-8

Molecular Weight

– C27H28N4O3S2

Compound Purity

– 0.9905

SMILES

– Cc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)ccc1-c1ccc(cc1)S(C)(=O)=O

Target

– Others

Pathway

– Ubiquitination

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.