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Nedaplatin

$32$248

Products Details

Product Description

– Nedaplatin (NSC 375101D) is a derivative of cisplatin and DNA damage agent.

Web ID

– HY-13700

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C2H8N2O3Pt

References

– [1]Kanzawa, F., et al., In vitro synergistic interactions between the cisplatin analogue nedaplatin and the DNA topoisomerase I inhibitor irinotecan and the mechanism of this interaction. Clin Cancer Res, 2001. 7(1): p. 202-9.|[2]Uchida, N., et al., Sequence-dependent antitumour efficacy of combination chemotherapy of nedaplatin, a novel platinum complex, with 5-fluorouracil in an in vivo murine tumour model. Eur J Cancer, 1998. 34(11): p. 1796-801.

CAS Number

– 95734-82-0

Molecular Weight

– 303.18

Compound Purity

– 98.0

SMILES

– O=C1C[O-][Pt+2](N)(N)[O-]1

Clinical Information

– Launched

Research Area

– Cancer

Solubility

– DMF : 1 mg/mL (ultrasonic)|H2O : 13.6 mg/mL (ultrasonic;warming)

Target

– DNA/RNA Synthesis

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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