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MIND4-19

$85$720

Products Details

Product Description

– MIND4-19 is a potent SIRT2 inhibitor with an IC50 value of 7.0 μM. MIND4-19 can be used for researching Huntington’s disease[1].

Web ID

– HY-147233

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C22H19N3OS

References

– [1]Quinti L, et al. SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington’s Disease Models. Cell Chem Biol. 2016 Jul 21;23(7):849-861.

CAS Number

– 129544-85-0

Molecular Weight

– 373.47

Compound Purity

– 99.94

SMILES

– C1(COC2=CC=CC=C2)=NN=C(SCC3=CC=CC=C3)N1C4=CC=CC=C4

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– DMSO : ≥ 100 mg/mL

Target

– Sirtuin

Isoform

– SIRT2

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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