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M3541

SKU T70873-1 mg Category Small Compound Brand: TargetMol

Price range: 829 CAD through 4,960 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– M3541 is a selectively potent and orally active ATM inhibitor with potential antitumor activity.M-3541 inhibits ATM kinase activity and ATM-mediated signaling by binding to ATM.M3541 prevents activation of DNA damage checkpoints, inhibits DNA damage repair, contributes to apoptosis, and induces death of ATM overexpressing tumor cells.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T70873

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H17FN6O2

References

– Waqar SN,et al. Phase I trial of ATM inhibitor M3541 in combination with palliative radiotherapy in patients with solid tumors. Invest New Drugs. 2022 Jun;40(3):596-605.

CAS Number

– 1360628-91-6

Molecular Weight

– C23H17FN6O2

Compound Purity

– 0.9897

SMILES

– O=C1N(C=2C=3C(=CC(OC)=C(C3)C4=CN(C)N=C4)N=CC2N1C)C5=C(F)C=C(C#N)C=C5

Pathway

– PI3K/Akt/mTOR signaling|||Apoptosis|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.