Lurasidone hydrochloride

SKU T1735-5 mg Category Brand:

Price range: 56 CAD through 795 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor antagonist, serotonin 5-HT7 receptor antagonist, an antagonist of the adrenergic α2A and α2C receptors, as well as a partial serotonin 5-HT1A receptor agonist. It is used in the [research relevance to related conditions].
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1735

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H36N4O2S·HCl

Citations

– 1. Danek P J, Daniel W A. The Atypical Antipsychotic Lurasidone Affects Brain but Not Liver Cytochrome P450 2D (CYP2D) Activity. A Comparison with Other Novel Neuroleptics and Significance for Drug Treatment of Schizophrenia. Cells. 2022, 11(21): 3513. 2. Kot M, Haduch A, Papp M, et al. The effect of chronic treatment with lurasidone on rat liver cytochrome P450 expression and activity in the chronic mild stress (CMS) model of depression. Drug Metabolism and Disposition. 2017, 45(12): 1336-1344 3. Danek P J, Wójcikowski J, Daniel W A. The atypical neuroleptics iloperidone and lurasidone inhibit human cytochrome P450 enzymes in vitro. Evaluation of potential metabolic interactions. Pharmacological Reports:PR. 2020, 72(6): 1685-1694 4. Danek P J, Daniel W A.The effect of new atypical antipsychotic drugs on the expression of transcription factors regulating cytochrome P450 enzymes in rat liver.Pharmacological Reports.2024: 1-7.

References

– Ishibashi T, et al. J Pharmacol Exp Ther, 2010, 334(1), 171-181.

CAS Number

– 367514-88-3

Molecular Weight

– C28H36N4O2S·HCl

Compound Purity

– 0.9951

SMILES

– Cl.O=C1[C@H]2[C@@H]3CC[C@@H](C3)[C@H]2C(=O)N1C[C@@H]1CCCC[C@H]1CN1CCN(CC1)c1nsc2ccccc12

Target

– Interleukin

Pathway

– GPCR/G Protein|||Neuroscience

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.