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Inauhzin

SKU T1887-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 56 CAD through 595 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Inauhzin (INZ)(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human Y cells without causing apparently genotoxic stress(IC50=3 uM, in A549 cell).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1887

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H19N5OS2

Citations

– 1. Sun Y, Yang Y M, Hu Y Y, et al. Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death. Redox Biology. 2022: 102334 2. Sun Y, Yang Y M, Hu Y Y, et al. Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death. Redox Biology. 2022: 102334

References

– Zhang Q, et al. EMBO Mol Med. 2012 Apr; 4(4): 298-31

CAS Number

– 309271-94-1

Molecular Weight

– C25H19N5OS2

Compound Purity

– 0.9829

SMILES

– CCC(Sc1nnc2c(n1)[nH]c1ccccc21)C(=O)N1c2ccccc2Sc2ccccc12

Target

– Others

Pathway

– Chromatin/Epigenetic|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.