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I-BET151
Price range: 66 CAD through 1,904 CAD
Products Details
Product Description
– I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 μM, in cell-free assays).
Web ID
– T2120
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H21N5O3
Citations
– 1. Maksylewicz A, Bysiek A, BET bromodomain inhibitors suppress inflammatory activation of gingival fibroblasts and epithelial cells from periodontitis patients. Frontiers in Immunology. 2019 Apr 30;10:933
2. Xiong C, Deng J, Wang X, et al. Pharmacologic Targeting of BET Proteins Attenuates Hyperuricemic Nephropathy in Rats. Frontiers in Pharmacology. 2021, 12: 147.
References
– Dawson MA, et al. Nature, 2011, 478(7370), 529-533.
CAS Number
– 1300031-49-5
Molecular Weight
– C23H21N5O3
Compound Purity
– 0.9903
SMILES
– Cl.COc1cc2c3n([C@H](C)c4ccccn4)c(=O)[nH]c3cnc2cc1-c1c(C)noc1C
Pathway
– Chromatin/Epigenetic
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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