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HBX 41108
Price range: 56 CAD through 1,000 CAD
Products Details
Product Description
– HBX 41108 (HBX-41108) is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBX 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
Web ID
– T21527
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C13H3ClN4O
References
– Colland F, Formstecher E, Jacq X, et al. Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells. Mol Cancer Ther, 2009, 8(8): 2286-2295.
CAS Number
– 924296-39-9
Molecular Weight
– C13H3ClN4O
Compound Purity
– 0.9913
SMILES
– Clc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N
Target
– Others
Pathway
– Apoptosis|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Ubiquitination
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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