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GS-9191

SKU T25466-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 173 CAD through 2,432 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– GS-9191 is a potent inhibitor of DNA polymerase alpha and ß, a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG), which penetrates the skin and is metabolized in the epithelium to an active nucleoside triphosphate analogue.GS-9191 has antiproliferative activity and reduces the size of papillomas in a dose-related manner.GS-9191 may be useful in the treatment of HPV-induced lesions.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T25466

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C37H51N8O6P

References

– Birkus G, et al. Role of cathepsin A and lysosomes in the intracellular activation of novel antipapillomavirus agent GS-919Antimicrob Agents Chemother. 2011;55(5):2166-73.

CAS Number

– 859209-84-0

Molecular Weight

– C37H51N8O6P

Compound Purity

– 0.9828

SMILES

– C(COCP(N[C@@H](CC1=CC=CC=C1)C(OCC(C)C)=O)(N[C@@H](CC2=CC=CC=C2)C(OCC(C)C)=O)=O)N3C=4C(=C(NC5CC5)N=C(N)N4)N=C3

Pathway

– Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.