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Products Details
Product Description
– Glycinexylidide (GX) is the active metabolite of Lidocaine. Lidocaine is a local anesthetic that inhibits sodium channels involving complex voltage and dependence. Lidocaine also reduces the growth, migration and invasion of gastric cancer cells. Glycinexylidide has research potential for use in anesthesia, cancer, and cardiovascular disease[1].
Web ID
– HY-W357818
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C10H14N2O
References
– [1]Strong JM, et al. Pharmacological activity, metabolism, and pharmacokinetics of glycinexylidide. Clin Pharmacol Ther. 1975 Feb;17(2):184-94.
CAS Number
– 18865-38-8
Molecular Weight
– 178.23
SMILES
– O=C(NC1=C(C)C=CC=C1C)CN
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ERK, MEK, NF-κB, Sodium Channel
Pathway
– MAPK/ERK Pathway, Membrane Transporter/Ion Channel, NF-κB, Stem Cell/Wnt
Product type
– Biochemical Assay Reagents
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
